{"id":2616,"date":"2016-08-05T18:17:00","date_gmt":"2016-08-05T18:17:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2616"},"modified":"2020-11-25T22:41:02","modified_gmt":"2020-11-25T22:41:02","slug":"chronic-hepatitis-c-virus-hcv-burden-in-rhode-island-modelling-treatment-scale-up-and-elimination","status":"publish","type":"post","link":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/chronic-hepatitis-c-virus-hcv-burden-in-rhode-island-modelling-treatment-scale-up-and-elimination\/","title":{"rendered":"Chronic hepatitis C virus (HCV) burden in Rhode Island: modelling treatment scale-up and elimination"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignleft size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"75\" height=\"100\" src=\"https:\/\/cdafound.org\/wp-content\/uploads\/2016\/08\/Epidemiology_and_Infection_Cover_08.2016_75x100.png\" alt=\"Journal Cover\" class=\"wp-image-3304\"\/><\/figure><\/div>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27492142\">Soipe AI, Razavi H, Razavi-Shearer D, Gal\u00e1rraga O, Taylor LE, Marshall BDL. Chronic hepatitis C virus (HCV) burden in Rhode Island: modelling treatment scale-up and elimination. Epidemiol Infect. 2016 Dec;144(16):3376-3386. doi: 10.1017\/S0950268816001722. Epub 2016 Aug 5. PMID: 27492142; PMCID: PMC5562531.<\/a><\/p>\n\n\n\n<br>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p>We utilized a disease progression model to predict the number of viraemic infections, cirrhotic cases, and liver-related deaths in the state of Rhode Island (RI) under four treatment scenarios: (1) current HCV treatment paradigm (about 215 patients treated annually, Medicaid reimbursement criteria fibrosis stage \u2a7eF3); (2) immediate scale-up of treatment (to 430 annually) and less restrictive Medicaid reimbursement criteria (fibrosis stage \u2a7eF2); (3) immediate treatment scale-up and no fibrosis stage-specific Medicaid reimbursement criteria (\u2a7eF0); (4) an &#8216;elimination&#8217; scenario (i.e. a continued treatment scale-up needed to achieve >90% reduction in viraemic cases by 2030). Under current treatment models, the number of cirrhotic cases and liver-related deaths will plateau and peak by 2030, respectively. Treatment scale-up with \u2a7eF2 and \u2a7eF0 fibrosis stage treatment criteria could reduce the number of cirrhotic cases by 21.7% and 10.0%, and the number of liver-related deaths by 19.3% and 7.4%, respectively by 2030. To achieve a >90% reduction in viraemic cases by 2030, over 2000 persons will need to be treated annually by 2020. This strategy could reduce cirrhosis cases and liver-related deaths by 78.9% and 72.4%, respectively by 2030. Increased HCV treatment uptake is needed to substantially reduce the burden of HCV by 2030 in Rhode Island.<\/p>\n\n\n\n<p><strong>Countries:<\/strong> United States &#8211; Rhode Island<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Soipe AI, Razavi H, Razavi-Shearer D, Gal\u00e1rraga O, Taylor LE, Marshall BDL. Chronic hepatitis C virus (HCV) burden in Rhode Island: modelling treatment scale-up and elimination. Epidemiol Infect. 2016 Dec;144(16):3376-3386. doi: 10.1017\/S0950268816001722. Epub 2016 Aug 5. PMID: 27492142; PMCID: PMC5562531. Summary We utilized a disease progression model to predict the number of viraemic infections, cirrhotic [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3303,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[31,10,12],"publication-author":[],"class_list":["post-2616","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-elimination","tag-hcv","tag-modelling"],"acf":[],"_links":{"self":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts\/2616","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/comments?post=2616"}],"version-history":[{"count":5,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts\/2616\/revisions"}],"predecessor-version":[{"id":3408,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts\/2616\/revisions\/3408"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/media\/3303"}],"wp:attachment":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/media?parent=2616"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/categories?post=2616"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/tags?post=2616"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/publication-author?post=2616"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}