{"id":2664,"date":"2014-05-05T21:40:00","date_gmt":"2014-05-05T21:40:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2664"},"modified":"2020-11-30T19:54:33","modified_gmt":"2020-11-30T19:54:33","slug":"strategies-to-manage-hepatitis-c-virus-hcv-disease-burden","status":"publish","type":"post","link":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/strategies-to-manage-hepatitis-c-virus-hcv-disease-burden\/","title":{"rendered":"Strategies to manage hepatitis C virus (HCV) disease burden"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignleft size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"75\" height=\"100\" src=\"https:\/\/cdafound.org\/wp-content\/uploads\/2018\/11\/JVH_GenericCover__75x100.png\" alt=\"Journal Cover\" class=\"wp-image-3191\"\/><\/figure><\/div>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24713006\">Wedemeyer H, Duberg AS, Buti M, Rosenberg WM, Frankova S, Esmat G, \u00d6rmeci N, Van Vlierberghe H, Gschwantler M, Akarca U, Aleman S, Bal\u0131k I, Berg T, Bihl F, Bilodeau M, Blasco AJ, Brand\u00e3o Mello CE, Bruggmann P, Calinas F, Calleja JL, Cheinquer H, Christensen PB, Clausen M, Coelho HS, Cornberg M, Cramp ME, Dore GJ, Doss W, El-Sayed MH, Erg\u00f6r G, Estes C, Falconer K, F\u00e9lix J, Ferraz ML, Ferreira PR, Garc\u00eda-Samaniego J, Gerstoft J, Giria JA, Gon\u00e7ales FL Jr, Guimar\u00e3es Pess\u00f4a M, H\u00e9zode C, Hindman SJ, Hofer H, Husa P, Idilman R, K\u00e5berg M, Kaita KD, Kautz A, Kaymakoglu S, Krajden M, Krarup H, Laleman W, Lavanchy D, L\u00e1zaro P, Marinho RT, Marotta P, Mauss S, Mendes Correa MC, Moreno C, M\u00fcllhaupt B, Myers RP, Nemecek V, \u00d8vrehus AL, Parkes J, Peltekian KM, Ramji A, Razavi H, Reis N, Roberts SK, Roudot-Thoraval F, Ryder SD, Sarmento-Castro R, Sarrazin C, Semela D, Sherman M, Shiha GE, Sperl J, St\u00e4rkel P, Stauber RE, Thompson AJ, Urbanek P, Van Damme P, van Thiel I, Vandijck D, Vogel W, Waked I, Weis N, Wiegand J, Yosry A, Zekry A, Negro F, Sievert W, Gower E. Strategies to manage hepatitis C virus (HCV) disease burden. J Viral Hepat. 2014 May;21 Suppl 1:60-89. doi: 10.1111\/jvh.12249. PMID: 24713006.<\/a><\/p>\n\n\n\n<br>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p>The number of hepatitis C virus (HCV) infections is projected to decline while those with advanced liver disease will increase. A modeling approach was used to forecast two treatment scenarios: (i) the impact of increased treatment efficacy while keeping the number of treated patients constant and (ii) increasing efficacy and treatment rate. This analysis suggests that successful diagnosis and treatment of a small proportion of patients can contribute significantly to the reduction of disease burden in the countries studied. The largest reduction in HCV related morbidity and mortality occurs when increased treatment is combined with higher efficacy therapies, generally in combination with increased diagnosis. With a treatment rate of approximately 10%, this analysis suggests it is possible to achieve elimination of HCV (defined as a >90% decline in total infections by 2030). However, for most countries presented, this will require a 3\u20135 fold increase in diagnosis and\/or treatment. Thus, building the public health and clinical provider capacity for improved diagnosis and treatment will be critical.<\/p>\n\n\n\n<p><strong>Countries:<\/strong> Australia, Austria, Belgium, Brazil, Czech Republic, Denmark, Egypt, England, France, Germany, Portugal, Spain, Sweden, Switzerland, Turkey<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wedemeyer H, Duberg AS, Buti M, Rosenberg WM, Frankova S, Esmat G, \u00d6rmeci N, Van Vlierberghe H, Gschwantler M, Akarca U, Aleman S, Bal\u0131k I, Berg T, Bihl F, Bilodeau M, Blasco AJ, Brand\u00e3o Mello CE, Bruggmann P, Calinas F, Calleja JL, Cheinquer H, Christensen PB, Clausen M, Coelho HS, Cornberg M, Cramp ME, Dore [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3193,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[10],"publication-author":[],"class_list":["post-2664","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-hcv"],"acf":[],"_links":{"self":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts\/2664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/comments?post=2664"}],"version-history":[{"count":5,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts\/2664\/revisions"}],"predecessor-version":[{"id":3444,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/posts\/2664\/revisions\/3444"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/media\/3193"}],"wp:attachment":[{"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/media?parent=2664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/categories?post=2664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/tags?post=2664"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/dnc-test.myddns.me\/cda-foundation\/cdafound.org\/wp-json\/wp\/v2\/publication-author?post=2664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}